NanoBrook Series

Characterizing proteins, nanoparticles, & polymers confronts users with a difficult choice of instrumentation. Brookhaven Instruments makes that choice easier with its NanoBrook series of products.

The Choice is Clear

Whether you need particle sizing capabilities including backscatter for proteins, zeta potential determination, or combinations of both including molecular weight determination of small polymers and proteins, Brookhaven offers a NanoBrook model which will fit your needs.

Particle Sizing Instruments

Select the NanoBrook 90Plus for sizing colloids and nanoparticles with diameters greater than 10 nm. The NanoBrook 173 is for sizing of globular proteins and small polymers as low as 1 nm hydrodynamic radius. Lastly, the NanoBrook 173Plus is used for sizing proteins, colloids, polymers and nanoparticles over the entire range.

Zeta Potential Instruments

The NanoBrook ZetaPlus is ideal for zeta potential determination of nanoparticles and colloids in water with salt concentrations less than 75 millimolar ionic strength. Select the NanoBrook ZetaPALS for zeta potential determination of proteins, nanoparticles, and colloids in water with salt concentrations up to 2 M ionic strength and in nonpolar or viscous liquids.

Combination Particle Sizing & Zeta Potential Instruments

For users who need both particle sizing and zeta potential analysis, we offer instruments with both capabilities.

The NanoBrook 90Plus PALS is used for sizing colloids and nanoparticles with diameters greater than 10 nm and for zeta potential determination of proteins, nanoparticles and colloids in water with salt concentrations up to 2 M ionic strength and in nonpolar or viscous liquids.

The NanoBrook 90Plus Zeta is used for zeta potential determination in water with salt concentrations up to 75 millimolar ionic strength and can also be used for the same particle sizing applications as the 90Plus and 90Plus PALS.

A Comprehensive, All-in-One Solution: NanoBrook Omni

Brookhaven’s NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer into one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilizes three measurement angles for truly unbiased measurement results.  The NanoBrook Omni utilizes a backscattering angle as well as 90° and 15°.

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Molecular Weight (5)
Particle Size (5)
Zeta Potential (5)
Particle Size
Between 100-900nm (1)
Less than 10nm (2)
Zeta Potential Application
High Salt (3)
Low Salt (3)