Exosomes are extracellular vesicles, typically 30 to 150 nanometers in diameter, that contain a specific composition of proteins, lipids, RNA, and DNA and are naturally released by cells into the extracellular environment. Exosomes play a crucial role in cell-to-cell communication by transferring their cargo from one cell to another, influencing various physiological and pathological processes. They are also thought to be involved in cellular waste disposal.
Because of their ability to carry molecular information, exosomes are being extensively studied for their potential in diagnostics, as biomarkers for diseases, and as delivery vehicles for therapeutics.
In the paper entitled, “Characterization of Human Umbilical Cord Blood Mesenchymal Stem Cell-Derived Exosomes by Size and Zeta Potential Analysis,” the authors used a Brookhaven Instruments NanoBrook 90Plus Zeta instrument to characterize the size and charge of hUCB-MSC exosomes. Characterization of exosome size and charge is essential as these parameters provide key information about their stability and biological interactions. The paper established the reliability of the NanoBrook dynamic light scattering and zeta potential instrument in the characterization of exosomes.
Brookhaven Instruments, with a legacy of pioneering in light scattering and zeta potential analysis, is committed to advancing its technology to provide reliable and innovative solutions that support modern scientific breakthroughs in nanotechnology, pharmaceuticals, and materials science.
Contact us today to learn more about our light scattering solutions for particle size and zeta potential analysis.