In the study, “Egg Yolk Granule Nanoparticles as Bioactive Nanocarriers for Curcumin Delivery: Intrinsic Hypolipidemic Activity and Combined Efficacy in Obese Mice,” chicken egg yolk granule (EYG) nanoparticles (EYG NPs) have enhanced effects when loaded with curcumin. Egg yolk granule nanoparticles are natural complexes of protein and lipid. Modifications to these nanoparticles can enhance their […]
In the rapidly evolving world of nanotechnology, pharmaceuticals, and materials science, understanding the size and behavior of nanoparticles is crucial. Dynamic Light Scattering (DLS,) also known as Photon Correlation Spectroscopy (PCS,) has emerged as a gold standard technique for particle size analysis, offering unparalleled accuracy and ease of use. If you’re looking to elevate your […]
Dynamic Light Scattering (DLS) measures the hydrodynamic size of particles in solution by analyzing their Brownian motion. When analyzing polystyrene latex particles (or other particles with a surface charge,) adding salt is crucial to ensure accurate and reproducible results. Why Salt is Added: Brookhaven Instruments, with a legacy of pioneering in light scattering and zeta potential analysis, is committed to advancing […]
Particle size distribution (PSD) is a critical parameter in numerous scientific and industrial applications, including pharmaceuticals, nanotechnology, materials science, and environmental monitoring. Accurate measurement of PSD enables better understanding of material properties, performance, and stability. Among the various techniques available, Dynamic Light Scattering (DLS) has emerged as a preferred method due to its non-invasive nature, […]
Nanoscale Research Letters, an open access journal published under Springer Open, presented a study entitled “Development of Dextran Nanoparticles for Stabilizing Delicate Proteins.” In this study, a Brookhaven NanoBrook 90Plus Particle Size Analyzer was used to help develop a novel approach to stabilize and encapsulate proteins into dextran nanoparticles. The process in conducting this research […]
Aging is a natural, unavoidable process. As people age, their bodies go through a number of physical and chemical changes. One systemic change is the increased aggregation of proteins in tissues, decreasing solubility, though the reasons for this are unknown. In a paper entitled, Role of Carbonyl Modifications on Aging-Associated Protein Aggregation, researchers explored the […]
Dynamic Light Scattering (DLS) is widely used for particle size analysis and protein characterization, but in addition to these core applications it also has some less common, innovative applications. Popular and emerging applications of dynamic light scattering include: Brookhaven Instruments, with a legacy of pioneering in light scattering and zeta potential analysis, is committed to […]
Transferosomes are a sophisticated type of vesicular carrier system designed to enhance drug delivery through the skin. They are ultra-deformable liposomes that can adapt their shape to penetrate the skin’s layers effectively, primarily driven by the hydration gradient in the skin. This unique flexibility allows transferosomes to traverse the skin barrier more efficiently than conventional liposomes. […]
Exosomes are extracellular vesicles, typically 30 to 150 nanometers in diameter, that contain a specific composition of proteins, lipids, RNA, and DNA and are naturally released by cells into the extracellular environment. Exosomes play a crucial role in cell-to-cell communication by transferring their cargo from one cell to another, influencing various physiological and pathological processes. […]
Light scattering technologies for quantum dot characterization