Application Library

Using Uncertainty Analysis to Optimize GPC System Performance (from Boston ACS meeting, 2010)

Introduction GPC when coupled with Static Light Scattering (SLS) is a fairly modern and powerful technique for determining absolute molecular weight values without the need to rely on traditional column calibration. In GPC-SLS the signal intensity levels rather than elution times are evaluated quantitatively. In addition, unlike in polymer standard calibration, details of the accurate […]

Applications: ChromatographyPolymers
Instruments: BI-DNDCBI-MwA

Zooming in on Zeta Potential

The determination of electrophoretic mobility and zeta potential is crucial to understanding the behavior and stability of colloids and suspensions over time. Traditional light scattering methods that are based upon the shifted frequency spectrum are relatively insensitive and can fail when confronted with high viscosity oils, non-polar liquids, high salt concentrations or particles that are […]

Applications: NanoParticlesTitrations
Instruments: NanoBrook SeriesBI-SM50

Advances in Zeta Potential Measurement of Proteins Using the ZetaPALS

Introduction Stability of protein formulations is of critical importance for the rapidly emerging areas of protein therapeutics and vaccine production from recombinant antigens. Zeta potential is the surface charge density at the shear plane, is one of the parameters used in predicting the stability of these preparations. Zeta potential has also been used as an […]

Applications: PolymersZeta
Instruments: NanoBrook Series

Brookhaven’s NanoBrook 90Plus Particle Analyzer Used to Study Alumina Nanofluids

“Particle Shape Effects On Thermophysical Properties Of Alumina Nanofluids” a study conducted by Elena Timofeeva, Jules Routbort and Dileep Singh, was featured in the Journal of Applied Physics. In this study, the researchers used Brookhaven’s NanoBrook 90Plus Particle Size Analyzer to determine dynamic light scattering (DLS) measurements of the nanofluids. This enabled them to investigate […]

Applications: ColloidsComplex FluidsNanoParticles
Instruments: NanoBrook Series

Research on English Ivy Nanoparticles Uses Brookhaven’s BI-200SM Goniometer

A feature in Nano Express entitled, “Ultraviolet Extinction and Visible Transparency by Ivy Nanoparticles” investigated the optical absorption and scattering properties of nanoparticles secreted by English ivy with the help of Brookhaven’s BI-200SM Goniometer. Quanshui Li, Lijin Xia and Zhili Zhang and Mingjun Zhang through this research, explored the diverse properties and potential applications of […]

Applications: NanoParticles
Instruments: BI-200SM

BI-200SM Goniometer Used in Nanoparticle Dynamic Light Scattering

In the study entitled “Strain specificity in Antimicrobial Activity of Silver and Copper Nanoparticles,” four strains of Escherichia coli, three strains of each Bacillus subtilis and Staphylococcus Aureus were used to assess the antimicrobial properties of silver and copper nanoparticles. The Brookhaven BI-200SM Goniometer was used in particle size measurement of suspended nanoparticles via dynamic light scattering (DLS). Bacterial experiments […]

Applications: Emulsions
Instruments: BI-200SM

Brookhaven’s BI-200SM Aids in Research on Local Phospholipid Environment

The Journal of Biological Chemistry featured a research study entitled “The Local Phospholipid Environment Modulates the Activation of Blood Clotting”, conducted by Andrew Shaw and his colleagues. In this study, the researchers made use of Brookhaven’s BI-200SM Goniometer to aid them in their investigation of the local changes in phospholipid bilayer composition and how this […]

Applications: Biopharma
Instruments: BI-200SM

Nano-Composites at University of Sussex

The Brookhaven Instruments BI-DCP Disc Centrifuge is providing to be crucial piece of equipment for a group of polymer researchers led by, Dr. Steve Armes. The team, based at the University of Sussex in the UK, is developing new polymer nanocomposite particles for a range of important uses including better ways to diagnose deadly illnesses […]

Applications: NanoParticles
Instruments: BI-DCP

Clarkson University praises Brookhaven Instruments

Researchers at Clarkson University in New York have recently praised the Brookhaven equipment they use in their laboratories for its capabilities. The Department of Chemical Engineering routinely uses a NanoBrook ZetaPALS and a BI-200SM Research Goniometer with a BI-9000AT Autocorrelator for its work and Adjunct Professor Chris Brancewicz explained, “There are a tremendous number of […]

Applications: Civil EngineeringZeta
Instruments: BI-200SMTurboCorr

Drug Delivery System: Micelle for Water-Insoluble Drugs

Vitamin E TPGS, d-α-tocopherol polyethylene glycol 1000 succinate, is a surfactant that can be used for drug delivery. TPGS has a molecular structure of a typical amphiphile. Due to its large lipophilic and hydrophilic portions, the Critical Micelle Concentration (CMC) is relatively low. Thus, it is a good emulsifier for a wide range of water-oil […]

Applications: BiopharmaDrug Delivery
Instruments: NanoBrook Series