Automation of pH-titrations using the BI-ZTU
The Brookhaven Instruments Autotitrator (BI-ZTU) provides researchers with a tool to study the effect of pH on zeta potential (ζ).
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Posted on: Nov 25, 2020
Why are DLS Measurements at High Concentration Difficult?
Despite the versatility of the DLS technique, there are several important considerations that cannot be ignored when using light scattering to characterize high-concentration solutions.
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Posted on: Nov 18, 2020
Why is Ionic Strength Relevant to DLS Measurements?
The measurement of particle size by dynamic light scattering (DLS) is heavily dependent on the stability of materials being investigated. Interactions between simple, spherical, colloidal particles are most frequently described by a balance between attractive and repulsive interactions.
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Posted on: Nov 12, 2020
Data analysis and distribution weighting: FAQ for DLS users
Dynamic Light Scattering (DLS) is a popular technique for obtaining size distributions of dispersible colloidal particles as well as other nanomaterials. As with all other light scattering based techniques, the intensity of scattered light is strongly skewed towards larger particles, something that must be considered when analyzing samples with two or more major constituents.
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Posted on: Oct 29, 2020
Static Light Scattering of Biomacromolecules: MW of Protein Samples Measured with the BI-200SM
Static Light Scattering (SLS) is capable of measuring the average molecular weight of polydisperse materials, as well as of samples with discrete aggregation numbers, such as proteins.
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Posted on: Sep 2, 2020
Optimizing GPC performance: Multi-Angle Static Light Scattering detection using the BI-MwA
Gel-permeation chromatography (GPC) coupled with Multi-Angle Static Light Scattering (SLS) is a modern and powerful technique for determining absolute molecular weight values without the need to rely on traditional column calibration.
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Posted on: May 28, 2020
Guide to Making Useful Measurements of Monoclonal Antibodies (mAbs) with Dynamic Light Scattering
Summary Dynamic light scattering (DLS) is a powerful technique that is amenable to measurement of biological samples, particularly proteins and biopolymers. One of the fastest growing classes of pharmaceutically active biologics are antibodies. These highly versatile proteins are used as the major functional element in immunoassays and other rapid diagnostics, in vaccine production, and as […]
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Posted on: Apr 15, 2020
The X-ray Disc Centrifuge – A Unique Particle Sizing Technique
Summary Disc centrifuges fractionate particles according to both size and density, making them ideal for high-resolution particle sizing. X-Ray based detection further simplifies the process of calculating a particle size distribution from a centrifugation-based instrument, eliminating optical corrections and approximations. This has been shown to be especially relevant for metal particles and metal oxide, which […]
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Posted on: Jan 29, 2020
ZetaPALS Brochure
Zeta Potential & Particle Size Analyzer For Measurements In: Solvents High Salt Oily or viscous media Near the isoelectric point 1,000x more sensitive than other techniques ZetaPALS: A Whole New Concept For measurements of low mobility, the unique, Brookhaven Instruments ZetaPALS is the answer. There is nothing else like it. With concepts developed at Bristol […]
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Posted on: Nov 8, 2019
Zeta potential measurement of limestone in seawater by Phase Analysis Light Scattering
Abstract Measurements of limestone in 100% seawater (1.15M ionic strength), 50% seawater, and 25% seawater were conducted on the Brookhaven Instruments NanoBrook ZetaPALS. Below is the procedure for preparing these samples as well as the measurement parameters used in their analyses. Introduction Zeta Potential is relatively easy to measure in cases of high charge and […]
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Posted on: Nov 8, 2019