Application Library

Brookhaven’s BI-MwA Aids in Probe for a New Water Soluble Polymer

Istanbul Technical University’s Department of Chemistry presented a study investigating the kinetics of polymerization of N-allyl maleamic acid (AMA) in efforts to come up with a new polymer that would inhibit a cyclo-polymer formation. The study, entitled “New Water-Soluble Polymer With Allyl Pendant Groups” made use of Brookhaven’s BI-MwA Molecular Weight Analyzer through a light […]

Applications: Polymers
Instruments: BI-MwA

Analysis of Virus Particles in Media by Dynamic Light Scattering

Introduction Traditional visual methods of observing virus particles in solution give a snapshot of a very small sampling volume, while the technique of particle analysis using dynamic light scattering yields an ensemble average of particles present in the solutions. Virus particles incubated in the laboratory present a challenge, as they must be grown within cells […]

Applications: BiopharmaColloids
Instruments: NanoBrook Series

Brookhaven’s BI-200SM Used in Synthesizing Gold Nanoparticles

“Synthesis of Gold Nanoparticles Grafted with a Thermoresponsive Polymer by Surface-Induced Reversible-Addition-Fragmentation Chain-Transfer Polymerization” is a research study conducted by Janne Raula. It’s aim was to explore and demonstrate the synthesis of well-defined gold nanoclusters with a polymeric-coating. Additionally, it’s goal was to obtain a water-soluble MPC nanoparticle with an environmentally sensitive polymer layer that […]

Applications: NanoParticles
Instruments: BI-200SM

MIT Chooses Brookhaven Instruments Again For Particle Sizing

A research group in the Chemical Engineering Department at the Massachusetts Institute of Technology (MIT) in the USA has recently chosen the NanoBrook ZetaPALS Zeta Potential Analyzer from Brookhaven Instruments to replace an older Brookhaven Instruments particle sizing instrument. The lab studies problems associated with the controlled release of pharmaceuticals, and uses the ZetaPALS analyzer […]

Applications: Self-assembled
Instruments: NanoBrook Series

Disk Centrifuge with Biopolymers for Particle Sizing

The Research and Development department of Biocompatibles Ltd. in Farnham, Surrey, bought a BI-DCP Disc Centrigue from Brookhaven Instruments Ltd. to collect vital information needed to develop a new specialist material. Biocompatibles develops synthetic materials that mimic a cell’s biology in order to improve the biocompatibility of medical devices. Dr. Andy Lewis, Research and Technology […]

Applications: Polymers
Instruments: BI-DCP

Guide to Making Useful Measurements of Monoclonal Antibodies (mAbs) with Dynamic Light Scattering

Summary Dynamic light scattering (DLS) is a powerful technique that is amenable to measurement of biological samples, particularly proteins and biopolymers. One of the fastest growing classes of pharmaceutically active biologics are antibodies. These highly versatile proteins are used as the major functional element in immunoassays and other rapid diagnostics, in vaccine production, and as […]

Applications: BiopharmaDLSProteins
Instruments: NanoBrook SeriesBI-200SM

Brookhaven Instruments Fundamental in Characterizing Unknown Polymer

The Physics Department at the College of Wooster presented a study which investigated the effective diameter, polydispersity and average molecular weight of an unknown polymer in the solution phase using static and dynamic light scattering techniques as recorded by Brookhaven Instruments Software. The study was conducted by Katherine Frato and was entitled, “Characterization of an […]

Applications: Polymers
Instruments: BI-200SM

Eindhoven University of Technology Uses Brookhaven’s BI-DCP on Research

Eindhoven University of Technology’s Laboratory of Polymer Chemistry presented a study entitled “Polybutadiene latex particle size distribution analysis utilizing a disk centrifuge.” They discussed Polybutadiene latexes made in emulsifier-free emulsion polymerization of both unimodal and bimodal particles size distributions, which were analyzed through the line-start (LIST) method using a Brookhaven Disk Centrifuge Photosedimentometer (DCP). Results […]

Applications: NanoParticles
Instruments: BI-DCP

Manchester Materials Science Research

The Manchester Materials Science Center at the University of Manchester and UMIST are conducting leading-edge polymer science research using a BI-9000AT light scattering correlator and BI-DCP Disc Centrifuge, both from Brookhaven Instruments Ltd. Peter Lovell, Professor of Polymer Science, acted on recommendations from people already using the equipment. “The good service and back up offered […]

Applications: Polymers
Instruments: TurboCorr

Research on TB Vaccine breakthrough used Brookhaven’s NanoBrook ZetaPlus

BMC Immunology, an open access journal, published a study entitled “Evaluation Of Specific Humoral Immune Response And Cross Reactivity Against Mycobacterium Tuberculosis Antigens Induced In Mice Immunized With Liposomes Composed Of Total Lipids Extracted From Mycobacterium Smegmatis”. Maria De los Angeles Garcia and her colleagues aimed to demonstrate the potential of a liposome formulation composed […]

Applications: BiopharmaZeta
Instruments: NanoBrook Series