Application Library

The X-ray Disc Centrifuge – A Unique Particle Sizing Technique

Summary Disc centrifuges fractionate particles according to both size and density, making them ideal for high-resolution particle sizing. X-Ray based detection further simplifies the process of calculating a particle size distribution from a centrifugation-based instrument, eliminating optical corrections and approximations.  This has been shown to be especially relevant for metal particles and metal oxide, which […]

Applications: Sizing
Instruments: BI-XDCBI-DCP

Introducing the Sample Filtration System

The sample filtration system from Brookhaven Instruments, the BI-SFS, is a fast and convenient method of cleaning all light scattering samples. Using Teflon tubing and non-reactive components, the system is compatible with almost all filtration needs. Its modular design allows users to change pump heads and speeds to tackle virtually any application. Dust in samples […]

Applications: Sample Prep
Instruments: BI-SFS
image of Zeta PALS

ZetaPALS Brochure

Zeta Potential & Particle Size Analyzer For Measurements In: Solvents High Salt Oily or viscous media Near the isoelectric point 1,000x more sensitive than other techniques ZetaPALS: A Whole New Concept For measurements of low mobility, the unique, Brookhaven Instruments ZetaPALS is the answer. There is nothing else like it. With concepts developed at Bristol […]

Applications: Zeta
Instruments: NanoBrook Series

Zeta potential measurement of limestone in seawater by Phase Analysis Light Scattering

Abstract Measurements of limestone in 100% seawater (1.15M ionic strength), 50% seawater, and 25% seawater were conducted on the Brookhaven Instruments NanoBrook ZetaPALS. Below is the procedure for preparing these samples as well as the measurement parameters used in their analyses. Introduction Zeta Potential is relatively easy to measure in cases of high charge and […]

Applications: High SaltOil RecoveryPetrochemicals
Instruments: NanoBrook Series

Using Uncertainty Analysis to Optimize GPC System Performance (from Boston ACS meeting, 2010)

Introduction GPC when coupled with Static Light Scattering (SLS) is a fairly modern and powerful technique for determining absolute molecular weight values without the need to rely on traditional column calibration. In GPC-SLS the signal intensity levels rather than elution times are evaluated quantitatively. In addition, unlike in polymer standard calibration, details of the accurate […]

Applications: ChromatographyPolymers
Instruments: BI-DNDCBI-MwA

Molecular Weight of PVP with the BI-MwA

Library Polyvinylpyrrolidone (PVP) a Molecular Weight Determination with the BI-MwA Polyvinylpyrrolidone (PVP) is a polar molecule and is used in a wide variety of applications. For example, since it simply passes through humans, it is a binder in pharmaceutical tablets. Because PVP binds to polar molecules quite well, it is also used as a paper […]

Applications: Polymers
Instruments: BI-MwA

Molecular Weight of PLA with the BI-MwA

Polylactic Acid (Polylactide, PLA) Molecular Weight Determination with the BI-MwA Polylactic acid, (polylactide, PLA) polymers are being used in a wide range of biomedical, commercial, pharmaceutical and academic applications due to their biocompatibility and biodegradability. Applications include stents, sutures and a wide range of uses in food packaging and disposable tableware. However, the molecular weight […]

Applications: Polymers
Instruments: BI-MwA

Advances in Zeta Potential Measurement of Proteins Using the ZetaPALS

Introduction Stability of protein formulations is of critical importance for the rapidly emerging areas of protein therapeutics and vaccine production from recombinant antigens. Zeta potential is the surface charge density at the shear plane, is one of the parameters used in predicting the stability of these preparations. Zeta potential has also been used as an […]

Applications: PolymersZeta
Instruments: NanoBrook Series

How the NanoBrook Instrument can be a Valuable Academic Teaching Tool

Abstract The NanoBrook line of instruments for particle size and zeta potential analysis while a powerful and all-encompassing research aid used throughout the world can also be used for teaching purposes in many undergraduate and non-technical settings where the principles of dynamic light scattering and electrophoretic mobility are important. Introduction Many times throughout the year, […]

Applications: Teaching
Instruments: NanoBrook Series

Guide for DLS sample preparation

Nomenclature The term solvent refers the pure solvent used to prepare the diluent. Examples of solvents are toluene or water. The diluent may also be referred to as the liquid in DLS textbooks. Diluents are solvent with additives, for example a 10% by weight methanol in water or a 10 mM KNO3 salt in DI […]

Applications: DLSSample PrepTheory
Instruments: NanoBrook Series
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