Application Library

Brookhaven’s NanoBrook ZetaPALS Aids in Synthesizing Nanomagnetic Particle for Magnetic Hyperthermia

BioMed Central featured a study entitled, “Physically Synthesized Ni-Cu Nanoparticles For Magnetic Hyperthermia”, authored by Martin Bettge, Jhunu Chatterjee and Yousef Haik. The goal of the study was to demonstrate how self-regulating magnetic hyperthermia could be achieved by synthesizing nanomagnetic particles with desired Curie temperature. The process used in this study was composed of melting […]

Applications: NanoParticles
Instruments: NanoBrook Series

MIT Chooses Brookhaven Instruments Again For Particle Sizing

A research group in the Chemical Engineering Department at the Massachusetts Institute of Technology (MIT) in the USA has recently chosen the NanoBrook ZetaPALS Zeta Potential Analyzer from Brookhaven Instruments to replace an older Brookhaven Instruments particle sizing instrument. The lab studies problems associated with the controlled release of pharmaceuticals, and uses the ZetaPALS analyzer […]

Applications: Self-assembled
Instruments: NanoBrook Series

Advances in Zeta Potential Measurement of Proteins Using the ZetaPALS

Introduction Stability of protein formulations is of critical importance for the rapidly emerging areas of protein therapeutics and vaccine production from recombinant antigens. Zeta potential is the surface charge density at the shear plane, is one of the parameters used in predicting the stability of these preparations. Zeta potential has also been used as an […]

Applications: PolymersZeta
Instruments: NanoBrook Series

BASF chooses Brookhaven again for chemicals research

BASF Agro Research, which develops chemicals for use in agriculture, has purchased a NanoBrook ZetaPALS from Brookhaven Instruments, based on Phase Analysis Light Scattering (PALS), for the determination of zeta potential of colloidal suspensions. Zeta potential is a useful indicator of a formulation’s stability. The new instrument has a particle sizing option based on DLS […]

Applications: Zeta
Instruments: NanoBrook Series

Colloidal Stability in Aqueous Suspensions

Why too much dispersant causes problems. Abstract Zeta potential in aqueous suspensions is a function of two variables: charge at the shear plane and free salt ion concentration. [Free here means not attached to the particle surface.] If a dispersant is added to increase the surface charge density (increase stability) and it’s too concentrated, the […]

Applications: ColloidsFormulations
Instruments: NanoBrook Series

Pursuing Purer Water

Microelectrophoresis helps optimize U.K. coagulation treatment. Tightening regulations are presenting new challenges for the United Kingdom’s water treatment and distribution companies. In recent years, there has been a considerable reinforcement of water quality regulations with new World Health Organization guidelines being published in 1993 and the recent revision of the European Union Drinking Water Directive. […]

Applications: HealthWater Treatment
Instruments: NanoBrook Series

Use of Zeta Potential Measurements to Characterize Good and Bad Inks

Zeta Potential of Printing Inks Offers Insights into Performance Inks for high-quality applications are frequently applied using a process by which a series of rollers acquire ink selectively according to a pattern formed on their surfaces and then transfer this ink to the printable substrate. This process is controlled by a combination of mechanically and […]

Applications: ColloidsFormulationsZeta
Instruments: NanoBrook Series

BSA Monomer-Dimer Elucidation with the BI-MwA

Aggregation kills. Aggregated therapeutic proteins can provoke immune response and have reduced therapeutic effect. This has led to regulatory and industrial interest in identifying aggregates for elimination. Size-exclusion chromatography (SEC/GPC) has been a useful technique for the determination of molecular weights of proteins. However, its usefulness is limited by the requirement for calibration of the […]

Applications: BiopharmaChromatographyMolecular Weight
Instruments: BI-MwA

The X-ray Disc Centrifuge – A Unique Particle Sizing Technique

Summary Disc centrifuges fractionate particles according to both size and density, making them ideal for high-resolution particle sizing. X-Ray based detection further simplifies the process of calculating a particle size distribution from a centrifugation-based instrument, eliminating optical corrections and approximations.  This has been shown to be especially relevant for metal particles and metal oxide, which […]

Applications: Sizing
Instruments: BI-XDCBI-DCP

Colloid Measuring Company, Nanolytics, Calls on Brookhaven Instruments

Nanolytics, a German company offering service measurements of colloid systems to the chemical and pharmaceutical industries, has recently added Brookhaven Instruments BI-200SM Research Goniometer with a BI-9000AT Autocorrelator to its range of laboratory instruments. Dr. Kristian Schilling, who founded the company explained, ” I set up Nanolytics because of an increasing demand for a competent […]

Applications: ColloidsNanoParticles
Instruments: BI-200SM
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