By Bruce B. Weiner Ph.D. Introduction: Zeta potential is a useful property to know for colloids, nanoparticles, and proteins. It is a substitute for the otherwise hard to measure surface charge. The zeta potential is not equal to the surface potential but rather it is the electrostatic potential difference between a rotationally averaged point at the […]
Comparing the Effects of Two Different Lipophilic Surfactants on the Zeta Potential of CBD Nanoemulsions Cannabidiol, CBD, is a non-psychoactive chemical compound obtained from Cannabis sativa. CBD has many benefits including anti-inflammatory properties and neuropathic pain relief, which may be preferred over other pain-relieving methods due to its non-addictive characteristics. CBD is lipophilic oil and […]
Summary Cannabidiol, CBD, is a non-psychoactive chemical compound obtained from Cannabis sativa, more specifically the hemp plant. CBD has many benefits including anti-inflammatory properties and neuropathic pain relief, which may be preferred over other pain-relieving methods due to its non-addictive characteristics. Furthermore, CBD can be helpful in managing anxiety and mood disorders, improving sleep, and […]
Introduction Some particle size instruments determine size for individual particles. They are single particle counters. Some instruments determine surface area as a function of particle size. Some instruments determine mass or volume vs size. And some instruments determine various functions of scattered light intensity as a function of size. All can produce particle size distributions. […]
Summary The purpose of this guide is to demonstrate the proper method for preparing a zeta potential validation sample used for checking the performance of the NanoBrook ZetaPlus, ZetaPALS, 90PlusPALS, and Omni instrumentation. The BI-ZR5 validation material is a dark blue, inorganic powder that is insoluble in water. It has a mean particle size of […]
Brookhaven Instruments Corporation has been pioneering advancements in particle characterization instrumentation for 40 years. To celebrate this milestone we spoke to one of Brookhaven’s founders, Dr. Bruce Weiner, about the company’s inception and earlier years. Can you name a few scientists that have inspired you in your life or career? “Let’s start with Prof. Carl […]
In the previous entry in this series of papers on particle size and size distribution, the main features of the differential and cumulative size distribution functions were defined and discussed using continuous distributions. Continuous distributions can be measured approximately in fractionation experiments† where, for example, data is taken every second as fractionated slices of the […]
Particle size distribution data can be presented numerically (tabular format) or graphically. When presented graphically, there are two types: differential and cumulative. They are related. If one differentiates the cumulative distribution curve, the differential distribution is obtained. If one integrates the differential distribution curve, the cumulative distribution is obtained. Differential Distribution The differential distribution shows […]